Mastitis is the costliest disease in milk production worldwide, with approximately 70 to 80% of the economic losses caused by subclinical mastitis1.
Staphylococcus aureus is a key contagious dairy pathogen and a common cause of subclinical mastitis. It is notorious for being difficult to treat successfully and for avoiding detection due to its habit of shedding bacteria into milk only intermittently or not at all.
Subclinical mastitis is typified by decreased milk production and increased somatic cell counts, but in contrast to clinical mastitis, without any visible changes (e.g. flecks or swelling) to the milk or udder.2
Contagious mastitis can be spread from cow to cow through milking equipment or via contact with farm workers’ hands or cleaning cloths, before a dairy farmer is even aware an infection exists within the herd.
This is especially true in subclinical cases, where there are no obvious signs of infection. Even chronic infections (present for more than two months) can remain subclinical and can continue to spread throughout a herd undetected.
The StaphGold™ ELISA test is the most accurate test available for detecting contagious S. aureus mastitis using herd test milk samples. It allows effective, timely detection and management of infected cows to limit the impact on farm revenue and animal health.
StaphGold™ ELISA TEST
Intended for use on high-SCC herd test (i.e. milk recording) samples.
The StaphGold™ ELISA test can be used as part of routine herd testing /milk recording, so there is no extra time or effort involved in sample collection for farmers or vets. It is conducted on pooled quarter milk samples with a high somatic cell count, which are being analysed in the laboratory already.
To request the test, farmers simply subscribe to their nominated herd testing or milk recording lab beforehand to screen all high cell-count herd test samples using the StaphGold™ ELISA test. At each herd test, farmers (and their vets) will be notified of Staphylococcus aureus-infected animals, so that these animals can be managed to prevent further spread i.e. milked last. It is unlikely that treatment will be required, but it may be necessary, and this should be determined on veterinary advice.
S.aureus infections can be difficult to identify using conventional mastitis tests, which rely on detecting the pathogens themselves in milk samples. This is because S. aureus only sheds bacteria into milk intermittently, or not at all.
In contrast, the StaphGold™ ELISA test detects antibodies, which are biomarkers of the animal’s immune response to an S. aureus infection. This means of detection allows the StaphGold™ test to provide a level of accuracy that other S. aureus tests cannot.
Being able to screen high-SCC herd test samples at a high degree of sensitivity enables a number of valuable benefits, including:
The test is designed for use on at least two herd tests each lactation, so that multiple data points can be obtained. More than one positive result per animal per season is strongly indicative of infection being present.
The StaphGold™ ELISA test is less expensive than other conventional, less accurate S. aureus tests on the market. It also gives farmers the option to test for S. aureus only, when more expensive multiplex-pathogen tests do not.
Affordability is a key factor in supporting farmers to confidently request that all of their high SCC animals be screened for S. aureus infection. We are serious about helping farmers protect their revenue and animal welfare from the impacts of contagious mastitis.
StaphGold™ RAPID FARMSIDE TEST
A point-of-care rapid lateral flow test for detecting clinical S. aureus infections in less than 10 minutes. This test is under development in the USA. Watch this space!
- Reneau JK, Packard VL (1991) Monitoring mastitis, milk quality andeconomic losses in dairy fields. Dairy, Food, Environ Sanit 11: 4–11.
Seegers H, Fourichon C, Beaudeau F (2003) Production effects related tomastitis and mastitis economics in dairy cattle herds. Vet Res 34: 475–491
- Harmon, R. J. 1994. Physiology of mastitis and factors affecting somatic cellcounts. J. Dairy Sci. 77:2103–2112.